spectrum

Whole-genome treasure links new genes and variants to autism |  Spectrum |  Autism Research News

Whole-genome treasure links new genes and variants to autism | Spectrum | Autism Research News

The largest analysis to date of whole-genome sequences from people with autism links new genes and variants to the disease. The results and sequences – from 5,100 people with autism and 6,212 without – are on a cloud-based platform and are available to trained researchers. This effort is the latest advancement of the ongoing MSSNG …

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Many mouths making conversation, with speech bubbles in red and blue.

Community newsletter: Sexual prejudice; formation of synapses; convergence of genes | Spectrum | Autism Research News

Illustration by Laurene Boglio Three new autism research threads drew a slew of congratulatory tweets this week. Let’s dive in! A 16-part thread, by Alessandro Gozzi, a senior scientist at the Italian Institute of Technology in Rovereto, Italy, describes a mechanism behind the sex bias in autism, featured in a preprint his team published on …

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Image displaying impeded interneuron development.

‘Assembloids’ expose autism-linked genes that impede neuron development | Spectrum | Autism Research News

New platform: CRISPR experimentation reveals genes, such as LNPK, that impede the development of interneurons when they are absent from forebrain assembloid models. About 10% of genes strongly linked to autism and other neurodevelopmental conditions interfere with the development of interneurons, according to unpublished findings published on bioRxiv. The study gleaned the effects of genes …

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Synchronize chaos across a narrow slice of the spectrum

Synchronize chaos across a narrow slice of the spectrum

Conceptual overview of the coupling scheme between a chaotic master and slave oscillator via a bandpass filter, and the resulting complex interdependence between their activities. Credit: Chaos, solitons and fractals (2022). DOI: 10.1016/j.chaos.2022.112854 The abstract notion that the whole can be found in every part of something has long fascinated engaged thinkers in all fields …

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